Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.59 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.59 |
| ▸ | CCR1 | P32246 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802820 | 0.93 | OPRL1 (0.58) | OPRM1OPRL1CCR1TACR2TACR1 | |
| SCHEMBL7802957 | 0.91 | TACR2 (0.66) | OPRM1OPRL1TACR2TACR1 | |
| SCHEMBL7811493 | 0.86 | TACR2 (0.57) | OPRM1OPRL1TACR2TACR1DRD4 | |
| SCHEMBL8588638 | 0.86 | TACR2 (0.69) | TACR2TACR1 | |
| SCHEMBL7802852 | 0.84 | DRD4 (0.62) | OPRM1MEN1DRD4KMT2ASIGMAR1 | |
| SCHEMBL7803126 | 0.83 | OPRM1 (0.62) | OPRM1OPRL1CCR1TACR2TACR1 | |
| SCHEMBL7812082 | 0.83 | TACR2 (0.62) | TACR2TACR1 | |
| SCHEMBL7811904 | 0.79 | TACR2 (0.56) | OPRL1TACR2TACR1 | |
| SCHEMBL7873763 | 0.78 | TACR2 (0.65) | TACR2TACR1 | |
| SCHEMBL7807754 | 0.77 | DRD4 (0.58) | OPRM1OPRL1MEN1DRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773929-B1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORP (US) | 2001-10-31 | — | — | EP | disclosed |
| US-5654316-A | Piperidine derivatives as neurokinin antagonists | SCHERING CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |