SCHEMBL7802935

SCHEMBL7802935

CCCCCCSCCCCN1CCCCCC1=O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.41
ALOX5 P09917 2/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
FAAH O00519 1/20 0.40
MGLL Q99685 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
ADRA1B P35368 2/20 0.38
PIK3CD O00329 1/20 0.37
HRH3 Q9Y5N1 1/20 0.36
GBA1 P04062 1/20 0.36
ADRA1A P35348 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9653498 1.00 GAA (0.42) GAARAB9AALOX5KMT2AMEN1
SCHEMBL10704838 0.95 RAB9A (0.41) GAARAB9AALOX5KMT2AMEN1
SCHEMBL7801906 0.95 RAB9A (0.42) GAARAB9AALOX5KMT2AMEN1
SCHEMBL28520481 0.94 GAA (0.42) GAARAB9AALOX5KMT2AMEN1
SCHEMBL9056711 0.94 ALOX5 (0.46) GAARAB9AALOX5KMT2AFAAH
SCHEMBL7801728 0.94 ALOX5 (0.46) GAARAB9AALOX5KMT2AFAAH
SCHEMBL5858660 0.92 ALOX5 (0.46) GAARAB9AALOX5KMT2AMEN1
SCHEMBL11847945 0.92 ALOX5 (0.46) GAARAB9AALOX5KMT2AMEN1
SCHEMBL11849011 0.92 ALOX5 (0.46) GAARAB9AALOX5KMT2AMEN1
SCHEMBL8967917 0.92 ALOX5 (0.46) GAARAB9AALOX5KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0555483-B1 PROCESS FOR PRODUCING AZACYCLOALKANE DERIVATIVE HISAMITSU PHARMACEUTICAL CO (JP) 2001-02-28 EP disclosed
US-5371238-A Reacting 1-/n-alkenyl/-azacycloalkan-2-one with alkyl mercaptan using free radical initiator, reducing, distilling to purify HISAMITSU PHARMACEUTICAL CO., INC. (JP) 1994-12-06 US disclosed
EP-0555483-A1 PROCESS FOR PRODUCING AZACYCLOALKANE DERIVATIVE Hisamitsu Pharmaceutical Co., Inc. (JP) 1993-08-18 EP disclosed