Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056711 | 1.00 | ALOX5 (0.46) | ALOX5RAB9APIK3CDADRA1BFAAH | |
| SCHEMBL9056157 | 0.97 | RAB9A (0.43) | ALOX5RAB9APIK3CDADRA1BKMT2A | |
| SCHEMBL9653498 | 0.94 | GAA (0.42) | ALOX5RAB9APIK3CDADRA1BFAAH | |
| SCHEMBL7802935 | 0.94 | GAA (0.42) | ALOX5RAB9APIK3CDADRA1BFAAH | |
| SCHEMBL9056134 | 0.94 | ALOX5 (0.43) | ALOX5RAB9APIK3CDFAAHMGLL | |
| SCHEMBL463370 | 0.94 | ALOX5 (0.43) | ALOX5RAB9APIK3CDFAAHMGLL | |
| SCHEMBL7801906 | 0.92 | RAB9A (0.42) | ALOX5RAB9APIK3CDADRA1BFAAH | |
| SCHEMBL430004 | 0.92 | ALOX5 (0.53) | ALOX5RAB9APIK3CDADRA1BFAAH | |
| SCHEMBL297738 | 0.92 | ALOX5 (0.53) | ALOX5RAB9APIK3CDADRA1BFAAH | |
| SCHEMBL297237 | 0.92 | ALOX5 (0.53) | ALOX5RAB9APIK3CDADRA1BFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555483-B1 | PROCESS FOR PRODUCING AZACYCLOALKANE DERIVATIVE | HISAMITSU PHARMACEUTICAL CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5371238-A | Reacting 1-/n-alkenyl/-azacycloalkan-2-one with alkyl mercaptan using free radical initiator, reducing, distilling to purify | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0555483-A1 | PROCESS FOR PRODUCING AZACYCLOALKANE DERIVATIVE | Hisamitsu Pharmaceutical Co., Inc. (JP) | 1993-08-18 | — | — | EP | disclosed |