Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477414 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL1341251 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL27952716 | 0.74 | ALDH1A1 (0.63) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL1342303 | 0.74 | ALDH1A1 (0.63) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL14476702 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL14460830 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL11347429 | 0.72 | SLC6A9 (0.48) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL5391410 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL3797745 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL6304163 | 0.72 | RAB9A (0.58) | ALDH1A1TDP1RAB9ANPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054314-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |