Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CFD | P00746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803834 | 0.85 | KMT2A (0.39) | KMT2ANR1H4MAPTCNR1CNR2 | |
| SCHEMBL6514020 | 0.84 | NR1H4 (0.45) | KMT2ANR1H4MAPTESR1LMNA | |
| SCHEMBL7414042 | 0.83 | ABL1 (0.54) | KMT2ANR1H4CFDMAPTABCB11 | |
| SCHEMBL1300248 | 0.82 | CYP3A4 (0.45) | KMT2AMAPTCNR1CNR2ALDH1A1 | |
| SCHEMBL23812315 | 0.81 | CFD (0.43) | CFDMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3979506 | 0.81 | KDM4E (0.59) | CFDMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3691064 | 0.80 | KMT2A (0.61) | KMT2ANR1H4CFDMAPTABCB11 | |
| SCHEMBL7803918 | 0.80 | LMNA (0.39) | KMT2AMAPTCNR1CNR2KDM4E | |
| SCHEMBL7803914 | 0.80 | LMNA (0.39) | KMT2AMAPTCNR1CNR2KDM4E | |
| SCHEMBL23812298 | 0.79 | CFD (0.42) | KMT2ACFDMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097117-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003975-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2000-01-27 | — | — | WO | disclosed |