Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 6/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944255 | 0.80 | FADS1 (0.45) | FADS1HTR6HSD11B1 | |
| SCHEMBL7805594 | 0.78 | FADS1 (0.48) | FADS1GRM2HTR6 | |
| SCHEMBL9016279 | 0.75 | FADS1 (0.79) | FADS1GRM2HTR6HSD11B1 | |
| SCHEMBL7770572 | 0.73 | GRM2 (0.54) | FADS1GRM2HTR6 | |
| SCHEMBL7776725 | 0.71 | FADS1 (0.60) | FADS1GRM2HTR6HSD11B1 | |
| SCHEMBL1268405 | 0.69 | HTR6 (0.55) | FADS1GRM2HTR6HSD11B1 | |
| SCHEMBL28023734 | 0.69 | FADS1 (0.60) | FADS1GRM2HTR6HSD11B1 | |
| SCHEMBL2830693 | 0.68 | GRM2 (0.74) | GRM2 | |
| SCHEMBL4953049 | 0.68 | SLC8A1 (0.61) | — | |
| SCHEMBL7775283 | 0.67 | FADS1 (0.65) | FADS1GRM2HTR6HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054314-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |