Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 4/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797244 | 0.80 | FADS1 (0.61) | FADS1KDM4EALDH1A1HTR6HSD11B1 | |
| SCHEMBL7803853 | 0.80 | FADS1 (0.55) | FADS1HTR6HSD11B1 | |
| SCHEMBL7805594 | 0.80 | FADS1 (0.48) | FADS1HTR7KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6559707 | 0.74 | HTR7 (0.46) | HTR7KDM4EALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL7807351 | 0.72 | FADS1 (0.55) | FADS1HTR6HSD11B1ROCK2ROCK1 | |
| SCHEMBL13311684 | 0.70 | L3MBTL1 (0.55) | HTR7KDM4EALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL9016279 | 0.68 | FADS1 (0.79) | FADS1HTR6HSD11B1ROCK2ROCK1 | |
| SCHEMBL6767953 | 0.67 | HTR7 (0.45) | HTR7KDM4EALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL7805578 | 0.67 | HTR7 (0.48) | HTR7KDM4EALDH1A1SMN1; SMN2DRD2 | |
| Hydrochloric Acid SCHEMBL6768275 | 0.66 | HTR7 (0.44) | HTR7KDM4EALDH1A1SMN1; SMN2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |