SCHEMBL780396

SCHEMBL780396

Cc1ccc(S(=O)(=O)O)cc1-c1ccc(F)cc1F

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.40
PTGS2 P35354 14/20 0.40
PTGS1 P23219 6/20 0.39
FFAR4 Q5NUL3 1/20 0.36
SCN9A Q15858 1/20 0.36
BRD4 O60885 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2888542 0.89 PTGS2 (0.42) PARP1PTGS2PTGS1FFAR4
SCHEMBL11324926 0.83 ALDH1A1 (0.45)
SCHEMBL780162 0.83 KMT2A (0.40) PTGS2PTGS1
SCHEMBL779010 0.83 PTGS2 (0.38) PARP1PTGS2PTGS1FFAR4
SCHEMBL778956 0.81 PTGS2 (0.50) PTGS2PTGS1FFAR4
SCHEMBL778650 0.78 PTGS2 (0.39) PARP1PTGS2PTGS1FFAR4
SCHEMBL776573 0.77 PTPN1 (0.42) PTGS2PTGS1
SCHEMBL776846 0.77 SLC9A1 (0.39) PTGS2PTGS1SCN9A
SCHEMBL1711828 0.77 PTGS2 (0.50) PARP1PTGS2PTGS1
SCHEMBL3163675 0.76 HDAC1 (0.43) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed