Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7798189 | 0.82 | KMT2A (0.52) | KMT2AALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL2849753 | 0.80 | HSD17B10 (0.61) | KMT2AGPR119ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7804158 | 0.80 | HTR1B (0.50) | GPR119SMN1; SMN2HTR1AHTR1BHTR1F | |
| SCHEMBL7804080 | 0.80 | KDM4E (0.52) | KMT2AGPR119ALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8021880 | 0.79 | HTR1B (0.49) | GPR119SMN1; SMN2HTR1AHTR1BHTR1F | |
| SCHEMBL7804909 | 0.74 | MEN1 (0.38) | KMT2AALDH1A1HTR1AHTR1BHTR1F | |
| SCHEMBL7805945 | 0.74 | DRD4 (0.49) | KMT2AALDH1A1KDM4EHTR1B | |
| Hydrochloric Acid SCHEMBL8033399 | 0.73 | PRMT5 (0.38) | KMT2AALDH1A1HTR1AHTR1BHTR1F | |
| Hydrochloric Acid SCHEMBL8037880 | 0.73 | DRD4 (0.48) | KMT2AALDH1A1KDM4ESMN1; SMN2HTR1B | |
| SCHEMBL7804939 | 0.71 | HTR1B (0.43) | GPR119SMN1; SMN2HTR1AHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1510034-A | Indazole compound, preparing method thereof and medicine composition containing the same | ɪά��ʵ���� | 2004-07-07 | — | — | CN | disclosed |
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| US-6046205-A | FOR TREATMENT OF VENOUS INSUFFICIENCY AND OF ASSOCIATED DISORDERS, AND ALSO IN THE TREATMENT OF MIGRAINE | ADIR ET COMPAGNIE (FR) | 2000-04-04 | — | — | US | disclosed |
| US-6020336-A | Indole and indazole compounds | LES LABORATOIRES SERVIER (FR) | 2000-02-01 | — | — | US | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |