Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352923 | 0.87 | GPR119 (0.58) | ALDH1A1LMNAMAPTMTORGPR119 | |
| SCHEMBL1868073 | 0.85 | L3MBTL1 (0.43) | KDM4ESMN1; SMN2LMNANPC1GPR119 | |
| SCHEMBL1868072 | 0.85 | L3MBTL1 (0.43) | KDM4ESMN1; SMN2LMNANPC1GPR119 | |
| SCHEMBL3352833 | 0.83 | MAPT (0.45) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3356604 | 0.81 | HTR1A (0.52) | SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7805956 | 0.81 | KDM4E (0.52) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3349251 | 0.81 | LMNA (0.44) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL29741245 | 0.81 | GLS (0.44) | SMN1; SMN2ALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL3388874 | 0.81 | GLS (0.44) | SMN1; SMN2ALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL2849753 | 0.80 | HSD17B10 (0.61) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1510034-A | Indazole compound, preparing method thereof and medicine composition containing the same | ɪά��ʵ���� | 2004-07-07 | — | — | CN | disclosed |
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| US-6046205-A | FOR TREATMENT OF VENOUS INSUFFICIENCY AND OF ASSOCIATED DISORDERS, AND ALSO IN THE TREATMENT OF MIGRAINE | ADIR ET COMPAGNIE (FR) | 2000-04-04 | — | — | US | disclosed |
| US-6020336-A | Indole and indazole compounds | LES LABORATOIRES SERVIER (FR) | 2000-02-01 | — | — | US | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |