Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371455 | 0.90 | PPARG (0.45) | PPARGFFAR1EPHX2F2F10 | |
| SCHEMBL9857070 | 0.89 | SLC6A9 (0.52) | PPARGFFAR1EPHX2F2F10 | |
| SCHEMBL7797631 | 0.88 | THRB (0.50) | PPARGFFAR1EPHX2F2F10 | |
| SCHEMBL27535203 | 0.84 | ESR1 (0.51) | ESR1ESR2F2F10KDM4E | |
| SCHEMBL8329187 | 0.83 | F2 (0.55) | ESR1ESR2F2F10 | |
| SCHEMBL13236836 | 0.83 | FFAR1 (0.46) | PPARGFFAR1KDM4EMEN1HSP90AA1 | |
| SCHEMBL6490172 | 0.82 | ESR1 (0.49) | ESR1ESR2PPARGFFAR1SLC6A9 | |
| SCHEMBL6533433 | 0.77 | F10 (0.47) | ESR1ESR2FFAR1F2F10 | |
| SCHEMBL6533437 | 0.77 | F10 (0.47) | ESR1ESR2FFAR1F2F10 | |
| SCHEMBL15687505 | 0.77 | ESR1 (0.50) | ESR1ESR2FFAR1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1236767-C | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2006-01-18 | — | — | CN | disclosed |
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |
| CN-1377269-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-10-30 | — | — | CN | disclosed |