Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804133 | 0.88 | ESR1 (0.48) | PPARGFFAR1EPHX2F2F10 | |
| SCHEMBL8371455 | 0.88 | PPARG (0.45) | THRBPPARGFFAR1EPHX2F2 | |
| SCHEMBL9857070 | 0.87 | SLC6A9 (0.52) | PPARGFFAR1EPHX2F2F10 | |
| SCHEMBL6491675 | 0.85 | FFAR1 (0.55) | BACE1PPARGFFAR1CACNA1ACACNA2D1 | |
| SCHEMBL13236833 | 0.84 | THRB (0.54) | THRBBACE1PPARGFFAR1CACNA1A | |
| SCHEMBL6179834 | 0.84 | F2 (0.53) | PPARGFFAR1F2LDHAPPARA | |
| SCHEMBL10665829 | 0.81 | L3MBTL1 (0.56) | THRBFFAR1F2F10ALOX15 | |
| SCHEMBL21199763 | 0.78 | FFAR1 (0.57) | THRBFFAR1F2F10ALOX15 | |
| SCHEMBL27532652 | 0.78 | F10 (0.45) | FFAR1F2F10LDHA | |
| SCHEMBL26639439 | 0.78 | LDHA (0.48) | PPARGEPHX2ALOX15LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1236767-C | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2006-01-18 | — | — | CN | disclosed |
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |
| CN-1377269-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-10-30 | — | — | CN | disclosed |