Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.77 |
| ▸ | CTSL | P07711 | 16/20 | 0.77 |
| ▸ | CTSB | P07858 | 15/20 | 0.77 |
| ▸ | CTSK | P43235 | 11/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1272977 | 0.95 | CTSS (0.79) | CTSSCTSLCTSBCTSK | |
| SCHEMBL3419281 | 0.92 | CTSS (0.65) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7801025 | 0.87 | CTSS (1.00) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2819290 | 0.86 | CTSS (0.78) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2819288 | 0.86 | CTSS (0.78) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2819285 | 0.86 | CTSS (0.78) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2821047 | 0.86 | CTSL (0.89) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2821048 | 0.86 | CTSL (0.89) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7803589 | 0.84 | CTSS (1.00) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7812607 | 0.84 | CTSS (1.00) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148488-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS FOR THE TREATMENT OF VARIOUS DISEASES | MERCK FROSST CANADA LTD. (CA) | 2010-12-29 | — | — | WO | disclosed |