Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8035169 | 0.99 | SIGMAR1 (0.43) | SIGMAR1TMEM97ABCB1GRIN1GRIN2B | |
| SCHEMBL7798311 | 0.84 | HTR1D (0.48) | — | |
| Hydrochloric Acid SCHEMBL8021858 | 0.83 | HTR1D (0.47) | — | |
| SCHEMBL7807115 | 0.82 | ABCB1 (0.61) | SIGMAR1TMEM97ABCB1HTR7 | |
| Hydrochloric Acid SCHEMBL8032751 | 0.82 | ABCB1 (0.60) | SIGMAR1TMEM97ABCB1HTR7 | |
| SCHEMBL7804936 | 0.81 | HTR1D (0.50) | — | |
| Hydrochloric Acid SCHEMBL8033639 | 0.80 | HTR1D (0.49) | — | |
| SCHEMBL7804951 | 0.79 | HTR1D (0.53) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8031090 | 0.78 | HTR1D (0.52) | SIGMAR1 | |
| SCHEMBL7804083 | 0.74 | SLC6A2 (0.49) | SIGMAR1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |