Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.46 |
| ▸ | HTR1B | P28222 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 2/20 | 0.41 |
| ▸ | PRKCB | P05771 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.41 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.41 |
| ▸ | STK16 | O75716 | 1/20 | 0.41 |
| ▸ | PAK3 | O75914 | 1/20 | 0.41 |
| ▸ | CDK14 | O94921 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8021805 | 0.99 | HTR1D (0.45) | HTR1DHTR1BL3MBTL1DRD4DRD2 | |
| SCHEMBL7804880 | 0.92 | HTR1D (0.46) | HTR1DHTR1BL3MBTL1DRD4DRD2 | |
| Hydrochloric Acid SCHEMBL8037826 | 0.91 | HTR1D (0.45) | HTR1DHTR1BL3MBTL1DRD4DRD2 | |
| SCHEMBL7804156 | 0.85 | DRD2 (0.48) | HTR1DHTR1BDRD4DRD2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8033624 | 0.84 | DRD2 (0.47) | HTR1DHTR1BDRD4DRD2SLC6A4 | |
| SCHEMBL4758506 | 0.82 | DRD2 (0.59) | L3MBTL1DRD4DRD2SLC6A4PRKCG | |
| SCHEMBL7804121 | 0.81 | HTR1D (0.44) | HTR1DHTR1BL3MBTL1DRD4KDM4E | |
| Hydrochloric Acid SCHEMBL8031546 | 0.81 | HTR1D (0.44) | HTR1DHTR1BL3MBTL1DRD4KDM4E | |
| Hydrochloric Acid SCHEMBL8172775 | 0.79 | HTR1D (0.45) | HTR1DHTR1BDRD2SLC6A4JAK3 | |
| SCHEMBL7798125 | 0.79 | HTR1D (0.56) | HTR1DHTR1BDRD4DRD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |