Sugi Predict

Sugi Predict / Compounds / SCHEMBL7784486

SCHEMBL7784486

SCHEMBL7784486

OC(Cl)(C(Cl)(Cl)Cl)C(Cl)(Cl)c1ccccc1C(Cl)(Cl)C(O)(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7787419 0.76 TSHR (0.50) TSHRALDH1A1MAPK1HIF1ACYP1A2
SCHEMBL7804375 0.71 TSHR (0.48) TSHRMAPK1HIF1A
SCHEMBL8145455 0.69 ALDH1A1 (0.46) TSHRALDH1A1TDP1CYP1A2
SCHEMBL82703 0.67 TSHR (0.44) TSHRALDH1A1TDP1MAPK1HIF1A
SCHEMBL30318973 0.65 TSHR (0.50) TSHRALDH1A1TDP1MAPK1CYP1A2
SCHEMBL545083 0.65 TSHR (0.50) TSHRALDH1A1TDP1MAPK1CYP1A2
SCHEMBL18242253 0.65 ALDH1A1 (0.33) TSHRALDH1A1TDP1
SCHEMBL27651539 0.65 ALDH1A1 (0.54) TSHRALDH1A1TDP1HIF1ACYP1A2
SCHEMBL4592612 0.65 KCNN4 (0.46) TSHRALDH1A1TDP1MAPK1HIF1A
SCHEMBL18243604 0.64 ALDH1A1 (0.32) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0779337-B1 FLUORINE-CONTAINING EPOXY RESIN COMPOSITION HIGHLY SOLUBLE IN SOLVENTS CANON KK (JP) 2001-10-24 — — EP disclosed
EP-0779337-A1 FLUORINE-CONTAINING EPOXY RESIN COMPOSITION HIGHLY SOLUBLE IN SOLVENTS CANON KABUSHIKI KAISHA (JP) 1997-06-18 — — EP disclosed