Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812067 | 0.91 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AALOX5SMN1; SMN2 | |
| SCHEMBL13527170 | 0.90 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AALOX5SMN1; SMN2 | |
| SCHEMBL9883892 | 0.88 | TRPM8 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2RARA | |
| SCHEMBL7814183 | 0.86 | APP (0.45) | ALDH1A1MEN1KMT2AALOX5SMN1; SMN2 | |
| SCHEMBL8989405 | 0.86 | TRPM8 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL10309270 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AALOX5SMN1; SMN2 | |
| SCHEMBL8989480 | 0.84 | APEX1 (0.38) | ALDH1A1MEN1KMT2AHPGDNPSR1 | |
| SCHEMBL15450056 | 0.83 | CDC7 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2RARA | |
| SCHEMBL14432142 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AALOX5SMN1; SMN2 | |
| SCHEMBL8989402 | 0.83 | MAPT (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565450-A | PESTICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | claimed |
| EP-0675882-B1 | 5-ARYL-1,3-THIAZINE DERIVATIVES, MANUFACTURE THEREOF AND USE AS PESTICIDES | BAYER AG (DE) | 2001-11-14 | — | — | EP | disclosed |
| US-5565450-A | PESTICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |