Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9188004 | 0.96 | PDE4A (0.35) | PDE4ACYP1A2CYP2C19CFTRLMNA | |
| SCHEMBL9199029 | 0.88 | MAPK1 (0.41) | PDE4ACYP1A2CYP2C19CFTRLMNA | |
| SCHEMBL9190102 | 0.88 | PDE4A (0.47) | PDE4ACYP1A2CYP2C19CFTRLMNA | |
| SCHEMBL7804038 | 0.88 | CA12 (0.33) | PDE4ACYP1A2CYP2C19CFTRLMNA | |
| SCHEMBL9196741 | 0.88 | LMNA (0.44) | PDE4ACYP1A2CYP2C19LMNAMEN1 | |
| SCHEMBL7804018 | 0.87 | ALDH1A1 (0.35) | PDE4ACYP1A2CYP2C19CFTRLMNA | |
| SCHEMBL9188618 | 0.87 | LMNA (0.34) | PDE4ACYP1A2CYP2C19CFTRLMNA | |
| SCHEMBL9203663 | 0.84 | GAA (0.37) | PDE4ACYP1A2LMNAMEN1KMT2A | |
| SCHEMBL9201294 | 0.84 | POLB (0.43) | CYP1A2CYP2C19CFTRLMNAMEN1 | |
| SCHEMBL7806809 | 0.82 | CFTR (0.40) | PDE4ACYP1A2CYP2C19CFTRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572429-B1 | SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF | BASF AG (DE) | 2001-04-18 | — | — | EP | disclosed |
| EP-0469460-B1 | Herbicidal sulphonylureas, method for their preparation and intermediates | BASF AG (DE) | 1995-10-18 | — | — | EP | disclosed |
| EP-0469462-B1 | 2-Amino-(fluoroalkoxy-1,3,5-triazines) and method for their preparation | BASF AG (DE) | 1995-10-11 | — | — | EP | disclosed |
| EP-0470434-B1 | Trifluoro- resp. chlorodifluoromethoxy-1,3-5-triazine and process for their preparation | BASF AG (DE) | 1995-10-11 | — | — | EP | disclosed |
| US-5434124-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1995-07-18 | — | — | US | disclosed |
| US-5342939-A | 2-amino-4-fluoroalkoxy-1,3,5-triazines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |
| US-5280118-A | Trifluoro-and chlorodifluoromethoxy-1,3,5-triazines | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-18 | — | — | US | disclosed |
| EP-0572429-A1 | SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |
| US-5214143-A | 2-AMINO-4-FLUOROALKOXY-1,3,5-TRIAZINES AND THE PREPARATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| US-5194610-A | TRIFLUORO- AND CHLORODIFLUOROMETHOXY-1,3,5-TRIAZINES AND THE PREPARATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| US-5188657-A | Herbicides consisting of sulfonyl-1,3,5-triazin-2-ylureas | BASF AKTIENGESELLSCHAFT (DE) | 1993-02-23 | — | — | US | disclosed |
| WO-1992014715-A1 | SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-03 | — | — | WO | disclosed |
| EP-0470434-A2 | Trifluoro- resp. chlorodifluoromethoxy-1,3-5-triazine and process for their preparation | BASF Aktiengesellschaft (DE) | 1992-02-12 | — | — | EP | disclosed |
| EP-0469462-A1 | 2-Amino-(fluoroalkoxy-1,3,5-triazines) and method for their preparation | BASF Aktiengesellschaft (DE) | 1992-02-05 | — | — | EP | disclosed |
| EP-0469460-A1 | Herbicidal sulphonylureas, method for their preparation and intermediates | BASF Aktiengesellschaft (DE) | 1992-02-05 | — | — | EP | disclosed |