SCHEMBL9199029

SCHEMBL9199029

CNc1nc(OC)nc(OC(F)(F)Cl)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 4/20 0.39
LMNA P02545 3/20 0.39
PDE4A P27815 2/20 0.38
PDE7A Q13946 1/20 0.38
POLB P06746 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
TP53 P04637 1/20 0.35
ALOX15 P16050 1/20 0.35
ALDH1A1 P00352 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
TSHR P16473 1/20 0.34
GAA P10253 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
CHRNA7 P36544 1/20 0.32
CFTR P13569 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9188004 0.92 PDE4A (0.35) MAPK1SMN1; SMN2LMNAPDE4AMEN1
SCHEMBL7804789 0.88 PDE4A (0.39) MAPK1SMN1; SMN2LMNAPDE4APDE7A
SCHEMBL9197498 0.85 MAPK1 (0.42) MAPK1SMN1; SMN2MAPTLMNAPDE4A
SCHEMBL33144 0.82 MAPK1 (0.52) MAPK1SMN1; SMN2MAPTLMNAPDE4A
SCHEMBL9190102 0.81 PDE4A (0.47) SMN1; SMN2MAPTLMNAPDE4APDE7A
SCHEMBL7804038 0.81 CA12 (0.33) LMNAPDE4AMEN1KMT2AL3MBTL1
SCHEMBL9201294 0.81 POLB (0.43) MAPTLMNAPOLBMEN1KMT2A
SCHEMBL7804018 0.80 ALDH1A1 (0.35) MAPK1SMN1; SMN2LMNAPDE4APOLB
SCHEMBL9188618 0.80 LMNA (0.34) LMNAPDE4AMEN1KMT2AL3MBTL1
SCHEMBL7798118 0.79 TP53 (0.34) MAPK1MAPTLMNAPOLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469460-B1 Herbicidal sulphonylureas, method for their preparation and intermediates BASF AG (DE) 1995-10-18 EP disclosed
US-5188657-A Herbicides consisting of sulfonyl-1,3,5-triazin-2-ylureas BASF AKTIENGESELLSCHAFT (DE) 1993-02-23 US disclosed
EP-0469460-A1 Herbicidal sulphonylureas, method for their preparation and intermediates BASF Aktiengesellschaft (DE) 1992-02-05 EP disclosed