Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888092 | 0.84 | KDM4E (0.50) | SMN1; SMN2ALDH1A1HDAC2HDAC8HDAC6 | |
| SCHEMBL4885533 | 0.83 | HDAC2 (0.47) | ALDH1A1HDAC2HDAC8HDAC6RECQL | |
| SCHEMBL13825640 | 0.83 | MME (0.50) | HDAC2HDAC8HDAC6RECQLKDM4E | |
| SCHEMBL22331980 | 0.81 | RAB9A (0.67) | SMN1; SMN2ALDH1A1HDAC2HDAC8HDAC6 | |
| SCHEMBL5612230 | 0.81 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1HDAC2HDAC8HDAC6 | |
| SCHEMBL3456224 | 0.81 | RAB9A (0.67) | SMN1; SMN2ALDH1A1HDAC2HDAC8HDAC6 | |
| SCHEMBL24465203 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HDAC2HDAC8HDAC6 | |
| SCHEMBL18759281 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HDAC2HDAC8HDAC6 | |
| SCHEMBL7772333 | 0.79 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1HDAC2HDAC8HDAC6 | |
| SCHEMBL30674431 | 0.79 | MAPT (0.60) | SMN1; SMN2ALDH1A1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010037011-A1 | Process for forming an amide bond | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-11-01 | — | — | US | disclosed |