Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13825641 | 0.94 | TRPV1 (0.51) | MMEITGB3ITGA2BMMEL1HPGD | |
| SCHEMBL13825652 | 0.94 | TRPV1 (0.51) | MMEITGB3ITGA2BMMEL1HPGD | |
| SCHEMBL13825720 | 0.88 | ALDH1A1 (0.48) | MMEITGB3ITGA2BMMEL1HDAC2 | |
| SCHEMBL13744623 | 0.87 | MME (0.54) | MMEMMEL1HPGD | |
| SCHEMBL13825642 | 0.86 | ALDH1A1 (0.52) | MMEHPGDKDM4ELMNA | |
| SCHEMBL7804877 | 0.83 | SMN1; SMN2 (0.57) | HDAC2HDAC8HDAC6RECQLKDM4E | |
| SCHEMBL14611003 | 0.82 | CTRB1 (0.53) | LMNA | |
| SCHEMBL14392786 | 0.82 | CTRB1 (0.53) | LMNA | |
| SCHEMBL12009636 | 0.82 | HPGD (0.68) | MMEHPGDHDAC2HDAC8HDAC6 | |
| SCHEMBL4888092 | 0.82 | KDM4E (0.50) | ITGB3ITGA2BHPGDHDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309766-B2 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | Obschestvo S. Organichennoi Otvetstvennostiyu Pharmenterprises (RU) | 2012-11-13 | — | — | US | disclosed |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | PAH, MAOA, APEH | MME 634/4885ITGB3 4262/4885ITGA2B 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.