Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 8/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.40 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306572 | 0.95 | NPC1 (0.51) | NPC1GNAI3GNAO1GNAI1L3MBTL3 | |
| SCHEMBL7806938 | 0.84 | NPC1 (0.50) | NPC1GNAI3GNAO1GNAI1L3MBTL3 | |
| SCHEMBL11080 | 0.83 | GNAI3 (0.55) | NPC1GNAI3GNAO1GNAI1L3MBTL3 | |
| SCHEMBL7808404 | 0.82 | NPC1 (0.51) | NPC1GNAI3GNAO1GNAI1L3MBTL3 | |
| SCHEMBL12789716 | 0.81 | ALDH1A1 (0.63) | NPC1L3MBTL3L3MBTL1ALDH1A1LMNA | |
| SCHEMBL11923450 | 0.79 | NPC1 (0.49) | NPC1GNAI3GNAO1GNAI1L3MBTL3 | |
| SCHEMBL11196 | 0.78 | NPC1 (0.47) | NPC1GNAI3GNAO1GNAI1L3MBTL3 | |
| SCHEMBL7458529 | 0.78 | L3MBTL3 (0.49) | NPC1GNAI3GNAO1GNAI1L3MBTL3 | |
| SCHEMBL13673411 | 0.78 | L3MBTL3 (0.49) | NPC1GNAI3GNAO1GNAI1L3MBTL3 | |
| SCHEMBL13772767 | 0.75 | L3MBTL3 (0.53) | NPC1L3MBTL3L3MBTL1ALDH1A1CDYL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975631-B1 | 5-ARYL-3-(8-AZABICYCLO[3.2.1]OCT-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AS 5-HT4 RECEPTOR LIGANDS | SANOFI SYNTHELABO (FR) | 2001-10-04 | — | — | EP | disclosed |
| US-6255319-B1 | ANTISEROTONIN AGENT | SANOFI-SYNTHELABO (FR) | 2001-07-03 | — | — | US | disclosed |
| US-5929089-A | ANTISEROTONINE AGENT | SYNTHELABO (FR) | 1999-07-27 | — | — | US | disclosed |
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |