Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 8/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Capeserod SCHEMBL4707724 | 0.87 | HTR4 (0.45) | HTR4GPR55CNR1 | |
| Capeserod SCHEMBL399091 | 0.86 | HTR4 (0.44) | HTR4GPR55CNR1 | |
| SCHEMBL7810023 | 0.86 | CHRNA7 (0.38) | HRH3CHRNA7OPRM1OPRD1OPRK1 | |
| SCHEMBL7799598 | 0.85 | HTR4 (0.44) | HTR4 | |
| Bromide SCHEMBL7946667 | 0.84 | HTR4 (0.43) | HTR4 | |
| SCHEMBL7810030 | 0.83 | HRH3 (0.37) | HRH3CHRNA7OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL7946706 | 0.82 | CHRNA7 (0.36) | HRH3CHRNA7OPRM1OPRD1OPRK1 | |
| SCHEMBL7804890 | 0.78 | HTR4 (0.46) | HTR4 | |
| Hydrochloric Acid SCHEMBL7945299 | 0.77 | HTR4 (0.46) | HTR4 | |
| SCHEMBL8303718 | 0.77 | HTR4 (0.52) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975631-B1 | 5-ARYL-3-(8-AZABICYCLO[3.2.1]OCT-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AS 5-HT4 RECEPTOR LIGANDS | SANOFI SYNTHELABO (FR) | 2001-10-04 | — | — | EP | disclosed |
| US-6255319-B1 | ANTISEROTONIN AGENT | SANOFI-SYNTHELABO (FR) | 2001-07-03 | — | — | US | disclosed |