SCHEMBL8303718

SCHEMBL8303718

CN1CCC(n2nc(-c3cc(Cl)c(N)c4c3OCCO4)oc2=O)CC1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 17/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL8369649 0.99 HTR4 (0.51) HTR4
SCHEMBL8306432 0.88 HTR4 (0.53) HTR4
Hydrochloric Acid SCHEMBL8364693 0.87 HTR4 (0.52) HTR4
SCHEMBL8308109 0.86 HTR4 (0.48) HTR4
Bromide SCHEMBL8369628 0.85 HTR4 (0.47) HTR4
Capeserod SCHEMBL4707724 0.83 HTR4 (0.45) HTR4
SCHEMBL8308397 0.83 HTR4 (0.49) HTR4
Capeserod SCHEMBL399091 0.83 HTR4 (0.44) HTR4
SCHEMBL8307581 0.82 GPR55 (0.38) HTR4
SCHEMBL7804890 0.82 HTR4 (0.46) HTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863897-B1 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS SYNTHELABO (FR) 1999-06-16 EP disclosed