Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 11/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8031123 | 0.99 | HTR1D (0.43) | HTR1DHTR1BHTR6HTR2CHTR2A | |
| SCHEMBL7798270 | 0.77 | HTR1D (0.50) | HTR1DHTR1BKDR | |
| Hydrochloric Acid SCHEMBL8033522 | 0.76 | HTR1D (0.49) | HTR1DHTR1BKDR | |
| SCHEMBL7804940 | 0.76 | HTR2C (0.57) | HTR1DHTR1BHTR6HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL27397107 | 0.75 | SLC22A12 (0.31) | HTR1DHTR1BSLC22A12 | |
| Hydrochloric Acid SCHEMBL8035287 | 0.75 | HTR2C (0.56) | HTR1DHTR1BHTR6HTR2CHTR2A | |
| SCHEMBL7798188 | 0.73 | HTR2C (0.54) | HTR1DHTR1BHTR6HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL8031634 | 0.72 | HTR2C (0.52) | HTR1DHTR1BHTR6HTR2CHTR2A | |
| SCHEMBL7808748 | 0.72 | HTR1D (0.34) | HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL8031488 | 0.71 | HTR1D (0.53) | HTR1DHTR1BHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |