Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162895 | 0.81 | TSHR (0.40) | ALDH1A1SHBGNPSR1TSHRL3MBTL1 | |
| SCHEMBL24328850 | 0.81 | TSHR (0.40) | ALDH1A1SHBGNPSR1TSHRL3MBTL1 | |
| SCHEMBL29074641 | 0.80 | EPHX1 (0.48) | ALDH1A1SHBGNPSR1TSHRL3MBTL1 | |
| SCHEMBL27638033 | 0.80 | ALDH1A1 (0.47) | ALDH1A1SHBGNPSR1TSHRL3MBTL1 | |
| SCHEMBL27981154 | 0.79 | CES2 (0.39) | ALDH1A1NPSR1CES2CES1TSHR | |
| SCHEMBL24328845 | 0.79 | TSHR (0.38) | ALDH1A1SHBGNPSR1TSHRL3MBTL1 | |
| SCHEMBL23247540 | 0.79 | TSHR (0.38) | ALDH1A1SHBGNPSR1TSHRL3MBTL1 | |
| SCHEMBL1072314 | 0.79 | ALDH1A1 (0.36) | ALDH1A1SHBGNPSR1TSHRL3MBTL1 | |
| SCHEMBL27508584 | 0.73 | ALDH1A1 (0.48) | ALDH1A1SHBGNPSR1TSHRL3MBTL1 | |
| SCHEMBL21398841 | 0.72 | ALDH1A1 (0.37) | ALDH1A1HPGDCES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088009-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Technology Company B.V. (NL) | 2001-04-04 | — | — | EP | disclosed |
| WO-2000063261-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2000-10-26 | — | — | WO | disclosed |