SCHEMBL21398841

SCHEMBL21398841

CCOC(C(=O)C1CCCCC1)S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
NAAA Q02083 1/20 0.35
TSHR P16473 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
EPHX1 P07099 1/20 0.34
ENPP3 O14638 2/20 0.34
ENPP1 P22413 2/20 0.34
ENPP2 Q13822 2/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
HSD11B1 P28845 1/20 0.33
HPGD P15428 1/20 0.32
GAA P10253 1/20 0.32
FFAR1 O14842 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21396924 0.81 CES2 (0.37) ALDH1A1NAAATSHRL3MBTL1EPHX1
SCHEMBL21398839 0.78 CES2 (0.34) ALDH1A1TSHRL3MBTL1EPHX1ENPP3
SCHEMBL7805487 0.72 ALDH1A1 (0.39) ALDH1A1NAAATSHRL3MBTL1EPHX1
SCHEMBL21396824 0.71 ALDH1A1 (0.37) ALDH1A1NAAATSHRL3MBTL1EPHX1
SCHEMBL23921449 0.68 SMN1; SMN2 (0.38) ALDH1A1ENPP3ENPP1CES2CES1
SCHEMBL30231090 0.68 THRB (0.33) ALDH1A1L3MBTL1GAALMNA
SCHEMBL942071 0.66 ALDH1A1 (0.46) ALDH1A1TSHRL3MBTL1KMT2AMEN1
SCHEMBL2001451 0.66 ALDH1A1 (0.46) ALDH1A1TSHRL3MBTL1KMT2AMEN1
SCHEMBL26740148 0.66 CES2 (0.39) ALDH1A1NAAAEPHX1CES2CES1
SCHEMBL23143056 0.66 EPHX1 (0.42) ALDH1A1TSHRL3MBTL1EPHX1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032290-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2024-07-09 US disclosed
US-20210318616-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2021-10-14 US disclosed
US-11073762-B2 Actinic ray-sensitive or radiation sensitive resin composition, actinic raysensitive or radiation-sensitive film, pattern forming method, method for manufacturing electronic device, and photoacid generator FUJIFILM CORPORATION (JP) 2021-07-27 US disclosed
US-20190294043-A1 ACTINIC RAY-SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, ACTINIC RAYSENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND PHOTOACID GENERATOR FUJIFILM CORPORATION (JP) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11073762-B2 Actinic ray-sensitive or radiation sensitive resin composition, actinic raysensitive or radiation-sensitive film, pattern forming method, method for manufacturing electronic device, and photoacid generator PRKAR2A, PRKAR2B, RER1 ALDH1A1 2149/4885NAAA 791/4885TSHR 1063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.