Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 3/20 | 0.43 |
| ▸ | TGM1 | P22735 | 3/20 | 0.43 |
| ▸ | TGM6 | O95932 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805633 | 0.81 | CTSL (0.46) | TGM2CTSLCTSBCTSKF13A1 | |
| SCHEMBL1716392 | 0.81 | MAPT (0.45) | TGM2CTSLCTSBCTSKVCP | |
| SCHEMBL12561404 | 0.81 | MGLL (0.46) | TGM2VCPMAPTMEN1KMT2A | |
| SCHEMBL6209181 | 0.79 | KDM1A (0.50) | TGM2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL4363356 | 0.79 | MAPT (0.48) | CTSLCTSBCTSKVCPMAPT | |
| SCHEMBL14898019 | 0.78 | MAPT (0.54) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7829444 | 0.78 | PTGDR2 (0.44) | TGM2VCPMAPTMEN1KMT2A | |
| SCHEMBL20296254 | 0.78 | MAPT (0.50) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL1955176 | 0.78 | MAPT (0.62) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7810712 | 0.77 | MAPT (0.48) | MAPTMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788498-B1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-08-16 | — | — | EP | disclosed |
| US-5883093-A | TREATING MICROBIAL INFECTIONS IN WARM BLOODED ANIMALS, INCLUDING HUMANS | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| EP-0788498-A1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013502-A1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |