Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TGM2 | P21980 | 7/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 3/20 | 0.39 |
| ▸ | TGM1 | P22735 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | TGM6 | O95932 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805632 | 0.81 | TGM2 (0.46) | CTSLCTSBCTSKNPC1RAB9A | |
| SCHEMBL7815379 | 0.71 | NPC1 (0.42) | NPC1RAB9AELANECHRM3 | |
| SCHEMBL9231451 | 0.71 | NPC1 (0.42) | NPC1RAB9AELANECHRM3 | |
| SCHEMBL9231450 | 0.71 | NPC1 (0.42) | NPC1RAB9AELANECHRM3 | |
| SCHEMBL31481320 | 0.69 | SMN1; SMN2 (0.50) | NPC1RAB9ATGM2ELANEHSD11B1 | |
| SCHEMBL4510870 | 0.68 | CTSK (0.46) | CTSLCTSBCTSKHSD11B1ALDH1A1 | |
| SCHEMBL4510873 | 0.68 | CTSK (0.46) | CTSLCTSBCTSKHSD11B1ALDH1A1 | |
| SCHEMBL4390012 | 0.68 | DRD4 (0.65) | CHRM3DRD4 | |
| SCHEMBL6865672 | 0.68 | DRD4 (0.65) | CHRM3DRD4 | |
| SCHEMBL2412607 | 0.67 | CTSL (0.53) | CTSLCTSBCTSKTGM2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788498-B1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-08-16 | — | — | EP | disclosed |
| US-5883093-A | TREATING MICROBIAL INFECTIONS IN WARM BLOODED ANIMALS, INCLUDING HUMANS | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| EP-0788498-A1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013502-A1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |