Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.41 |
| ▸ | IDO1 | P14902 | 6/20 | 0.41 |
| ▸ | TDO2 | P48775 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815082 | 0.95 | ADORA2A (0.41) | ADORA2AADORA1IDO1TDO2ALDH1A1 | |
| SCHEMBL7805503 | 0.86 | MAOA (0.44) | ADORA2AADORA1IDO1TDO2ALDH1A1 | |
| SCHEMBL7805489 | 0.85 | IDO1 (0.41) | ADORA2AADORA1IDO1TDO2ALDH1A1 | |
| SCHEMBL7813039 | 0.85 | ALDH1A1 (0.43) | ADORA2AADORA1IDO1TDO2ALDH1A1 | |
| SCHEMBL7816639 | 0.83 | IDO1 (0.57) | ADORA2AADORA1IDO1TDO2ALDH1A1 | |
| SCHEMBL7813200 | 0.81 | MAOA (0.44) | ADORA2AADORA1IDO1TDO2ALDH1A1 | |
| SCHEMBL7811756 | 0.81 | IDO1 (0.41) | ADORA2AADORA1IDO1TDO2ALDH1A1 | |
| SCHEMBL7815043 | 0.80 | ALDH1A1 (0.43) | ADORA2AADORA1IDO1TDO2ALDH1A1 | |
| SCHEMBL7815486 | 0.80 | IDO1 (0.57) | IDO1TDO2ALDH1A1MAPTUSP8 | |
| SCHEMBL7805732 | 0.78 | IDO1 (0.43) | ADORA2AADORA1IDO1TDO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876356-B1 | USE OF TRICYCLIC 1,4-DIHYDRO-1,4-DIOXO-1H-NAPHTHALENE DERIVATIVES, RESULTING NOVEL COMPOUNDS AND THERAPEUTICAL USE THEREOF | INNOTHERA SA LAB (FR) | 2001-10-31 | — | — | EP | claimed |
| US-6262095-B1 | TREATMENT OF ILLNESS ASSOCIATED WITH AN ALTERATION IN VENOUS FUNCTION AND/OR INFLAMMATORY EDEMA | LABORATOIRE INNOTHERA (FR) | 2001-07-17 | — | — | US | disclosed |