Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.33 |
| ▸ | NADK | O95544 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806081 | 1.00 | SLC15A1 (0.66) | SLC15A1HDAC6ALDH1A1LMNATP53 | |
| SCHEMBL8176532 | 0.89 | SLC15A1 (0.54) | SLC15A1HDAC6ALDH1A1LMNATP53 | |
| SCHEMBL3545846 | 0.86 | ALDH1A1 (0.54) | SLC15A1HDAC6ALDH1A1LMNATP53 | |
| SCHEMBL3547093 | 0.86 | ALDH1A1 (0.54) | SLC15A1HDAC6ALDH1A1LMNATP53 | |
| SCHEMBL3545841 | 0.86 | ALDH1A1 (0.54) | SLC15A1HDAC6ALDH1A1LMNATP53 | |
| SCHEMBL30860092 | 0.85 | SLC15A1 (0.51) | SLC15A1HDAC6ALDH1A1LMNATP53 | |
| SCHEMBL8626734 | 0.83 | SLC15A1 (0.49) | SLC15A1HDAC6ALDH1A1LMNATP53 | |
| SCHEMBL8367473 | 0.82 | HDAC6 (0.69) | SLC15A1HDAC6LMNATP53MAPT | |
| SCHEMBL7635326 | 0.82 | HDAC6 (0.69) | SLC15A1HDAC6LMNATP53MAPT | |
| SCHEMBL7639605 | 0.82 | HDAC6 (0.69) | SLC15A1HDAC6LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307043-B1 | FOR TREATMENT OR PROPHYLAXIS OF HERPES VIRAL INFECTIONS | GLAXO WELLCOME INC. | 2001-10-23 | — | — | US | disclosed |
| US-20010003744-A1 | Therapeutic compounds | CHAMBERLAIN STANLEY DAWES (US) | 2001-06-14 | — | — | US | disclosed |
| US-6093698-A | 1-(2',3',5'-TRIACETYL-BETA-D-RIBOFURANOSYL),2-BROMO,5,6-DICHLORO -BENZIMIDAZOLE OR 1-(5'-ACETYL-BETA-D-RIBOFURANOSYL),2-BROMO,5,6-DICHLORO-BENZIMIDAZOLE; TREATING HERPES VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2000-07-25 | — | — | US | disclosed |
| US-6077832-A | FOR THERAPY AND PROPHYLAXIS OF HERPES VIRUS INFECTION | GLAXO WELLCOME INC. (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0769017-B1 | THERAPEUTIC COMPOUNDS | WELLCOME FOUND (GB) | 2000-05-24 | — | — | EP | disclosed |
| US-5998605-A | Antiviral benzimidazole nucleoside analogues and method for their preparation | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | disclosed |
| US-5712255-A | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-01-27 | — | — | US | disclosed |
| US-5705490-A | TREATMENT OF HERPES OR CYTOMEGALOVIRUS WITH BENZIMIDAZOLE DERIATIVES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-01-06 | — | — | US | disclosed |
| US-5665709-A | FOR TREATING A HERPES VIRAL INFECTION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1997-09-09 | — | — | US | disclosed |
| US-5654283-A | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1997-08-05 | — | — | US | disclosed |
| US-5646125-A | Polysubstituted benzimidazoles as antiviral agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1997-07-08 | — | — | US | disclosed |
| US-5574058-A | Polysubstituted benzimidazoles as antiviral agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-11-12 | — | — | US | disclosed |
| WO-1996001833-A1 | THERAPEUTIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-01-25 | — | — | WO | disclosed |
| EP-0556334-A4 | POLYSUBSTITUTED BENZIMIDAZOLES AS ANTIVIRAL AGENTS | UNIV MICHIGAN (US) | 1995-03-29 | — | — | EP | disclosed |
| US-5360795-A | Treating cytomegalo virus and herpes simplex viruses | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1994-11-01 | — | — | US | disclosed |
| WO-1994008456-A1 | POLYSUBSTITUTED BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1994-04-28 | — | — | WO | disclosed |
| EP-0556334-A1 | POLYSUBSTITUTED BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007867-A1 | POLYSUBSTITUTED BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1992-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003744-A1 | Therapeutic compounds | ZC3HAV1, HAVCR2, EIF2AK2 | SLC15A1 3489/4885HDAC6 78/4885ALDH1A1 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.