Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 9/20 | 0.35 |
| ▸ | CA12 | O43570 | 8/20 | 0.35 |
| ▸ | CA2 | P00918 | 8/20 | 0.35 |
| ▸ | CA1 | P00915 | 8/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3545846 | 0.91 | ALDH1A1 (0.54) | SLC15A1ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL3545841 | 0.91 | ALDH1A1 (0.54) | SLC15A1ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL3547093 | 0.91 | ALDH1A1 (0.54) | SLC15A1ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL7740690 | 0.85 | SLC15A1 (0.41) | SLC15A1ALDH1A1HDAC6 | |
| SCHEMBL7806086 | 0.83 | SLC15A1 (0.66) | SLC15A1ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL7806081 | 0.83 | SLC15A1 (0.66) | SLC15A1ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL30860092 | 0.83 | SLC15A1 (0.51) | SLC15A1ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL8146838 | 0.82 | LMNA (0.52) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL7632914 | 0.81 | ALDH1A1 (0.51) | SLC15A1ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL7634776 | 0.81 | ALDH1A1 (0.51) | SLC15A1ALDH1A1LMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840743-A | TREATING HERPES VIRUS, CYTOMEGALO VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-11-24 | — | — | US | disclosed |