Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20689399 | 0.85 | L3MBTL1 (0.49) | L3MBTL1ADORA2AADORA1PDE10AHSD17B10 | |
| SCHEMBL21227307 | 0.82 | TYK2 (0.47) | L3MBTL1ADORA2AADORA1PDE10AHSD17B10 | |
| SCHEMBL20688023 | 0.81 | TYK2 (0.53) | L3MBTL1ADORA2AADORA1PDE10AHSD17B10 | |
| SCHEMBL30557539 | 0.80 | L3MBTL1 (0.44) | L3MBTL1ADORA2AADORA1PDE10AHSD17B10 | |
| SCHEMBL21258494 | 0.78 | TYK2 (0.46) | L3MBTL1ADORA2AADORA1PDE10AHSD17B10 | |
| SCHEMBL20153301 | 0.77 | RECQL (0.60) | L3MBTL1ADORA2AADORA1PDE10AHSD17B10 | |
| SCHEMBL10275026 | 0.75 | CCR1 (0.50) | L3MBTL1HSD17B10LMNAGAACYP3A4 | |
| SCHEMBL12051490 | 0.73 | L3MBTL1 (0.46) | L3MBTL1ADORA2AADORA1PDE10AHSD17B10 | |
| SCHEMBL9645210 | 0.73 | ALOX5 (0.51) | — | |
| SCHEMBL4809458 | 0.73 | LMNA (0.58) | L3MBTL1HSD17B10LMNAGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119547-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | Syngenta Limited (GB) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000021928-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2000-04-20 | — | — | WO | disclosed |