Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476742 | 0.95 | TBXAS1 (0.59) | TBXAS1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL7303484 | 0.75 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL10749342 | 0.75 | TBXAS1 (0.72) | TBXAS1MEN1LMNAKMT2AGAA | |
| SCHEMBL7807908 | 0.74 | ESR1 (0.47) | MEN1LMNAKMT2A | |
| SCHEMBL6682415 | 0.73 | MEN1 (0.60) | MEN1LMNAKMT2A | |
| SCHEMBL10751448 | 0.71 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2AGAA | |
| SCHEMBL6678076 | 0.70 | KMT2A (0.52) | MEN1LMNAKMT2A | |
| SCHEMBL7296483 | 0.70 | TBXAS1 (0.86) | TBXAS1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL10749397 | 0.70 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2AGAA | |
| SCHEMBL10750647 | 0.70 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077931-A1 | BENZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES | AstraZeneca AB (SE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059959-A1 | BENZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES | ASTRAZENECA AB (SE) | 1999-11-25 | — | — | WO | disclosed |