SCHEMBL780652

SCHEMBL780652

c1ccc(-c2cccc3c2sc2c(-c4ccc5c6ccccc6n(-c6cccc(-c7ccc8c9ccccc9c9ccccc9c8c7)c6)c5c4)cccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALOX5 P09917 1/20 0.37
LIMK1 P53667 1/20 0.36
MAPK14 Q16539 1/20 0.33
PDE10A Q9Y233 1/20 0.32
PRKDC P78527 1/20 0.31
KMT2A Q03164 2/20 0.30
IL1R1 P14778 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL780559 0.98 ALOX5 (0.39) KDM4EATML3MBTL1ALOX5LIMK1
SCHEMBL780797 0.95 KDM4E (0.40) KDM4EATML3MBTL1ALOX5LIMK1
SCHEMBL16390276 0.94 ALOX5 (0.39) KDM4EATML3MBTL1ALOX5LIMK1
SCHEMBL16390727 0.94 L3MBTL1 (0.41) KDM4EATML3MBTL1ALOX5LIMK1
SCHEMBL780625 0.93 ALOX5 (0.39) KDM4EATML3MBTL1ALOX5LIMK1
SCHEMBL780536 0.93 ALOX5 (0.39) KDM4EATML3MBTL1ALOX5LIMK1
SCHEMBL15745735 0.92 ALOX5 (0.43) KDM4EATML3MBTL1ALOX5LIMK1
SCHEMBL780646 0.92 KDM4E (0.37) KDM4EATML3MBTL1ALOX5LIMK1
SCHEMBL10165719 0.91 L3MBTL1 (0.49) KDM4EATML3MBTL1ALOX5LIMK1
SCHEMBL17562288 0.91 ALOX5 (0.49) KDM4EATML3MBTL1ALOX5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160380211-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-12-29 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160380211-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 KDM4E 3917/4885ATM 2271/4885L3MBTL1 947/4885
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 KDM4E 3917/4885ATM 2271/4885L3MBTL1 947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.