Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809484 | 0.94 | MAPT (0.51) | MAPTALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL7800564 | 0.94 | MAPT (0.51) | MAPTALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL7800547 | 0.93 | MAPT (0.49) | MAPTALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL7809526 | 0.89 | ALDH1A1 (0.58) | MAPTALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL7800593 | 0.83 | ALDH1A1 (0.56) | MAPTALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL8322697 | 0.79 | ALDH1A1 (0.52) | MAPTALDH1A1MAPK1SMN1; SMN2HTT | |
| SCHEMBL18134021 | 0.76 | ALDH1A1 (0.48) | MAPTALDH1A1SMN1; SMN2TDP1HTT | |
| SCHEMBL8445302 | 0.75 | ALDH1A1 (0.51) | MAPTALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL8799965 | 0.73 | ALDH1A1 (0.46) | MAPTALDH1A1MAPK1SMN1; SMN2HTT | |
| SCHEMBL7811948 | 0.73 | ALDH1A1 (0.67) | MAPTALDH1A1MAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010005914-A1 | OXIDATION DYES | ANDREAS J. BITTNER | 2001-07-05 | — | — | US | disclosed |
| EP-0912160-A2 | OXIDATION DYES | Hans Schwarzkopf GmbH & Co. KG (DE) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998001106-A2 | OXIDATION DYES | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 1998-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010005914-A1 | OXIDATION DYES | AOC1, CBR3, KRT18 | MAPT 3633/4885ALDH1A1 26/4885MAPK1 817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.