Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18134021 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL8445302 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8799965 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL7213151 | 0.80 | ALDH1A1 (0.56) | ALDH1A1EGFRP2RX1AURKBALDH5A1 | |
| SCHEMBL12916012 | 0.79 | MAPT (0.62) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL7807252 | 0.79 | MAPT (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8522113 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8321723 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL7809526 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL9148847 | 0.77 | MAPT (0.58) | ALDH1A1EGFRMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990355-A | AN OXIDATIVE DYES FOR HAIR, FREE OF HYDROGEN PEROXIDE, EASIER TO USE, MILDER, AND BETTER TOLERATED BECAUSE THE COLOR DEVELOPMENT IS THROUGH AIR | HANS SCHWARZKOPF GMBH & CO. KG. (DE) | 1999-11-23 | — | — | US | disclosed |
| US-5676706-A | HYDROGEN PEROXIDE-FREE HAIR COLORS; COLORFASTNESS | HANS SCHWARZKOPF GMBH & CO. KG. (DE) | 1997-10-14 | — | — | US | disclosed |
| EP-0709365-A1 | Substituted 2,4-diaminophenols, process for their preparation and hair dyes containing them | Hans Schwarzkopf GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |