Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7582234 | 0.84 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9137548 | 0.84 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL8551875 | 0.83 | ALOX5 (0.59) | ALOX5PTGS1PTGS2 | |
| SCHEMBL12707332 | 0.82 | ALOX5 (0.52) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7802551 | 0.81 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9029002 | 0.80 | ALOX5 (0.70) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7814703 | 0.80 | ALOX5 (0.47) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7811953 | 0.80 | ALOX5 (0.66) | ALOX5 | |
| SCHEMBL8547366 | 0.79 | ALOX5 (0.52) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8781473 | 0.78 | ALOX5 (0.46) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787127-B1 | 5-LIPOXYGENASE INHIBITORS | PFIZER (US) | 2001-01-03 | — | — | EP | claimed |
| EP-0787127-B1 | 5-LIPOXYGENASE INHIBITORS | PFIZER (US) | 2001-01-03 | — | — | EP | disclosed |
| US-6063928-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, CARDIOTONIC AGENTS | PFIZER INC (US) | 2000-05-16 | — | — | US | disclosed |
| EP-0787127-A1 | 5-LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011911-A1 | 5-LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1996-04-25 | — | — | WO | disclosed |