SCHEMBL7807481

SCHEMBL7807481

CNc1cc(CCO)cc(-c2ccc[nH]2)c1N

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 3/20 0.33
CDK8 P49336 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6573351 0.79 TDP1 (0.40) CDK8
SCHEMBL7461077 0.76
SCHEMBL7805949 0.76 CDK2 (0.33) CDK2
SCHEMBL7806004 0.74 LTA4H (0.38)
SCHEMBL7812060 0.74 PTPN1 (0.39)
SCHEMBL7800924 0.73 ADRA1D (0.31)
SCHEMBL7467340 0.71 PLAU (0.37)
SCHEMBL7456329 0.71 MEN1 (0.36)
SCHEMBL7462747 0.70 PIK3CD (0.31)
SCHEMBL7808522 0.68 PDPK1 (0.35) CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed