Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808604 | 0.85 | HDAC1 (0.36) | LTA4HMAPTALDH1A1GAAKEAP1 | |
| SCHEMBL7807643 | 0.83 | ALDH1A1 (0.35) | LTA4HMAPTALDH1A1GAAKEAP1 | |
| SCHEMBL6573351 | 0.79 | TDP1 (0.40) | MAPTALDH1A1GAAHPGDIKBKB | |
| SCHEMBL7812179 | 0.76 | LTA4H (0.38) | LTA4HMAPTALDH1A1GAAKEAP1 | |
| SCHEMBL7456329 | 0.76 | MEN1 (0.36) | MAPTHSD17B10PRMT6IKBKBHDAC1 | |
| SCHEMBL7812060 | 0.74 | PTPN1 (0.39) | MAPTALDH1A1GAAKDM4EHPGD | |
| SCHEMBL7807481 | 0.74 | CDK2 (0.33) | — | |
| SCHEMBL7800924 | 0.73 | ADRA1D (0.31) | — | |
| SCHEMBL7467340 | 0.71 | PLAU (0.37) | HDAC1HDAC2HDAC3 | |
| SCHEMBL7461077 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |