Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.31 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.31 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807390 | 0.92 | ADRA1D (0.36) | ADRA1DADRA1AKDM4EHSD17B10BRD4 | |
| SCHEMBL7805924 | 0.85 | PTGER4 (0.41) | ADRA1DADRA1ACYP2C19KDM4EALDH1A1 | |
| SCHEMBL7807674 | 0.85 | ADRA1D (0.33) | ADRA1DADRA1A | |
| SCHEMBL7808816 | 0.82 | PTGER4 (0.40) | ADRA1DADRA1AMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL7800934 | 0.82 | ADRA1D (0.34) | ADRA1DADRA1AMAPK1 | |
| SCHEMBL7812485 | 0.80 | PRKCI (0.35) | ADRA1DADRA1AKDM4EMAPK1PRKCI | |
| SCHEMBL7808724 | 0.76 | EGFR (0.34) | ADRA1DADRA1ACYP2C19KDM4ECDK1 | |
| SCHEMBL7460027 | 0.76 | CYP2C19 (0.32) | CYP2C19KDM4EGLACDK1ALDH1A1 | |
| SCHEMBL6570922 | 0.75 | PTGDR2 (0.44) | CYP2C19KDM4EGLATOP2BMAPK1 | |
| SCHEMBL6571957 | 0.75 | PRSS1 (0.38) | KDM4EFCGR3BFCGR1AFCGR2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |