Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501114 | 0.90 | FFAR1 (0.49) | MAOBFFAR1LTA4HEPHX2PPARG | |
| SCHEMBL27533969 | 0.82 | PPARA (0.47) | MAOBFFAR1LTA4HEPHX2PTPN1 | |
| SCHEMBL27533972 | 0.78 | PPARG (0.42) | FFAR1LTA4HEPHX2PTPN1PPARG | |
| SCHEMBL27535223 | 0.78 | NR1H4 (0.47) | FFAR1PTPN1PPARGPPARAPPARD | |
| SCHEMBL27510388 | 0.77 | MAOB (0.53) | MAOBFFAR1LTA4HPPARGPPARA | |
| SCHEMBL6178570 | 0.77 | FFAR1 (0.52) | MAOBFFAR1LTA4HPTPN1PPARG | |
| SCHEMBL1822558 | 0.74 | ITGB3 (0.69) | — | |
| SCHEMBL6491209 | 0.73 | LTA4H (0.48) | MAOBFFAR1LTA4HEPHX2PPARG | |
| SCHEMBL7498912 | 0.73 | LTA4H (0.40) | FFAR1LTA4HEPHX2PTPN1PPARG | |
| SCHEMBL13643129 | 0.72 | MAOB (0.65) | MAOBFFAR1LTA4HPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |