Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGAV | P06756 | 4/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807986 | 0.90 | MAOB (0.49) | FFAR1PPARGPPARAPKMLTA4H | |
| SCHEMBL27533969 | 0.85 | PPARA (0.47) | FFAR1PPARGPPARAFFAR4LTA4H | |
| SCHEMBL6499280 | 0.85 | PKM (0.39) | FFAR1PKMITGB3ITGAV | |
| SCHEMBL6178570 | 0.84 | FFAR1 (0.52) | FFAR1PPARGPPARAPKMFFAR4 | |
| SCHEMBL27533972 | 0.81 | PPARG (0.42) | FFAR1PPARGPPARAFFAR4LTA4H | |
| SCHEMBL1822558 | 0.79 | ITGB3 (0.69) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6491209 | 0.76 | LTA4H (0.48) | FFAR1PPARGPPARAFFAR4LTA4H | |
| SCHEMBL6500369 | 0.76 | AKR1B1 (0.37) | PKM | |
| SCHEMBL7498912 | 0.76 | LTA4H (0.40) | FFAR1PPARGPPARALTA4HEPHX2 | |
| SCHEMBL6177774 | 0.76 | PKM (0.77) | FFAR1PPARGPPARAPKMFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1218005-B1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1218005-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1218005-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001017959-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-15 | — | — | WO | disclosed |