Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27988084 | 0.78 | IMPDH2 (0.39) | IMPDH2IMPDH1AURKAAURKBASH1L | |
| SCHEMBL2466401 | 0.77 | IDO1 (0.56) | IDO1AURKAAURKBINCENPCNR1 | |
| SCHEMBL7812274 | 0.77 | CDK2 (0.45) | IMPDH2IMPDH1IDO1ADORA2ACNR1 | |
| SCHEMBL7800967 | 0.77 | ITK (0.38) | IMPDH2IMPDH1CDK2 | |
| SCHEMBL7800798 | 0.77 | PDPK1 (0.39) | IDO1AURKAAURKBINCENPADORA2A | |
| Hydrochloric Acid SCHEMBL8099675 | 0.75 | PDPK1 (0.38) | IDO1AURKAAURKBINCENPADORA2A | |
| SCHEMBL7808514 | 0.75 | AXL (0.36) | IMPDH2IMPDH1ADORA2ACDK2 | |
| SCHEMBL7807475 | 0.75 | ALDH1A1 (0.39) | IDO1AURKAAURKBCDK2KDR | |
| SCHEMBL7800962 | 0.73 | ALDH1A1 (0.38) | IDO1AURKAAURKBINCENPADORA2A | |
| SCHEMBL3790053 | 0.73 | ALDH1A1 (0.52) | IDO1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |