Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 5/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808514 | 0.92 | AXL (0.36) | ITKPTGER4IMPDH2IMPDH1AXL | |
| SCHEMBL7812274 | 0.82 | CDK2 (0.45) | IMPDH2IMPDH1ALDH1A1CDK2 | |
| SCHEMBL7807475 | 0.80 | ALDH1A1 (0.39) | AXLKCNH3ALDH1A1CDK2 | |
| SCHEMBL6573372 | 0.79 | MALT1 (0.42) | ITKPTGER4NCF1KCNH3ALDH1A1 | |
| SCHEMBL6571144 | 0.78 | ADRB2 (0.44) | ITKPTGER4NCF1KCNH3ALDH1A1 | |
| SCHEMBL6574643 | 0.77 | PTGER4 (0.40) | ITKPTGER4SLC40A1NCF1KCNH3 | |
| SCHEMBL7808535 | 0.77 | IMPDH2 (0.35) | IMPDH2IMPDH1CDK2 | |
| SCHEMBL7808809 | 0.76 | S100B (0.32) | CDK2 | |
| SCHEMBL7808491 | 0.76 | PTGER4 (0.41) | PTGER4NCF1ALDH1A1MAPTCDK2 | |
| SCHEMBL7456616 | 0.76 | PTGER4 (0.36) | ITKPTGER4SLC40A1NCF1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |