Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808458 | 0.81 | CYP3A4 (0.42) | PCSK9ALDH1A1KDM4EGAACYP2A6 | |
| SCHEMBL7805906 | 0.75 | MAPK1 (0.30) | HSD17B10MAPK1 | |
| SCHEMBL7800845 | 0.75 | PRKCI (0.39) | PCSK9ALDH1A1KDM4EGAACYP2A6 | |
| SCHEMBL7812154 | 0.74 | MAPT (0.36) | GAAMAPK1POLBNPC1TDP1 | |
| SCHEMBL7800649 | 0.74 | CYP3A4 (0.45) | PCSK9ALDH1A1KDM4EGAACYP2A6 | |
| SCHEMBL6136899 | 0.72 | PDE10A (0.46) | PCSK9ALDH1A1KDM4EGAACYP2A6 | |
| SCHEMBL6871689 | 0.71 | PRKCI (0.39) | PCSK9ALDH1A1KDM4EGAACYP2A6 | |
| SCHEMBL5705031 | 0.70 | TSHR (0.42) | PCSK9ALDH1A1KDM4EGAACYP2A6 | |
| SCHEMBL7808589 | 0.70 | HTR1A (0.35) | PCSK9ALDH1A1KDM4EGAACYP2A6 | |
| SCHEMBL7812485 | 0.70 | PRKCI (0.35) | PCSK9ALDH1A1KDM4EGAACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |