Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808548 | 0.81 | PCSK9 (0.35) | CYP3A4ALDH1A1PCSK9PLA2G7CYP2A6 | |
| SCHEMBL26690411 | 0.79 | HTR1A (0.38) | ALDH1A1RIPK2PCSK9CYP2A6CYP2A13 | |
| SCHEMBL7807699 | 0.75 | RORC (0.32) | RORCMAPTMEN1KMT2AADRA1D | |
| SCHEMBL7809608 | 0.75 | MAPT (0.38) | RORCMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7806015 | 0.75 | GAA (0.41) | CYP3A4ALDH1A1RIPK2PCSK9RORC | |
| SCHEMBL7800845 | 0.74 | PRKCI (0.39) | CYP3A4ALDH1A1PCSK9PLA2G7CYP2A6 | |
| SCHEMBL6136899 | 0.71 | PDE10A (0.46) | CYP3A4ALDH1A1PCSK9CYP2A6CYP2A13 | |
| SCHEMBL14399953 | 0.71 | DYRK3 (0.42) | CYP3A4ALDH1A1PCSK9HSD17B10SMN1; SMN2 | |
| SCHEMBL6871689 | 0.70 | PRKCI (0.39) | CYP3A4ALDH1A1PCSK9CYP2A6CYP2A13 | |
| SCHEMBL7452833 | 0.70 | CYP3A4 (0.42) | CYP3A4ALDH1A1PLA2G7MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |