Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808789 | 1.00 | KMT2A (0.38) | KMT2ACTNNB1WNT3AIDO1ALDH1A1 | |
| SCHEMBL8487400 | 0.89 | CA1 (0.46) | KMT2ACTNNB1WNT3AALDH1A1MAPT | |
| SCHEMBL7814060 | 0.89 | CA1 (0.46) | KMT2ACTNNB1WNT3AALDH1A1MAPT | |
| SCHEMBL7807198 | 0.89 | PTGS2 (0.47) | PTGS2NPC1RAB9APTGS1 | |
| SCHEMBL7807200 | 0.89 | PTGS2 (0.47) | PTGS2NPC1RAB9APTGS1 | |
| SCHEMBL7887232 | 0.87 | PTGS2 (0.48) | ALDH1A1PTGS2PTGS1 | |
| SCHEMBL7802249 | 0.87 | PTGS2 (0.48) | ALDH1A1PTGS2PTGS1 | |
| SCHEMBL7802251 | 0.87 | PTGS2 (0.48) | ALDH1A1PTGS2PTGS1 | |
| SCHEMBL2126889 | 0.87 | AKR1C3 (0.46) | KMT2AALDH1A1MAPTPTGS2PTGS1 | |
| SCHEMBL7810541 | 0.87 | PTGS2 (0.47) | CTNNB1WNT3APTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891345-B1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | UNION PHARMA SCIENT APPL (FR) | 2001-08-16 | — | — | EP | disclosed |
| US-6180651-B1 | ANTIINFLAMMATORY AGENTS; ANALGESICS | BRISTOL-MYERS SQUIBB | 2001-01-30 | — | — | US | disclosed |