Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045249 | 0.84 | CETP (0.43) | CETP | |
| SCHEMBL27992304 | 0.79 | CETP (0.34) | CETP | |
| SCHEMBL11373090 | 0.78 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL1045250 | 0.76 | CETP (0.30) | CETP | |
| SCHEMBL14533547 | 0.75 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL11299703 | 0.75 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL878835 | 0.75 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL841367 | 0.75 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11407435 | 0.73 | — | — | |
| SCHEMBL841642 | 0.73 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015629-A | Processes for synthesizing 1-(2-ethylbutyl) cyclohexane carbonitrile | ALBEMARLE CORP | 2011-04-13 | — | — | CN | claimed |
| CN-104557356-B | The manufacture method of nitrile and its corresponding amine | 中国石油化工股份有限公司 | 2017-10-10 | — | — | CN | disclosed |
| US-9603816-B2 | Process | HOFFMANN-LA ROCHE INC. (US) | 2017-03-28 | — | — | US | disclosed |
| US-9603816-B2 | Process | HOFFMANN-LA ROCHE INC. (US) | 2017-03-28 | — | — | US | disclosed |
| EP-2274278-B1 | NEW PROCESS FOR THE PREPARATIION OF CYCLOHEXANECARBOXYLIC ACID DERICATIVES | HOFFMANN LA ROCHE (CH) | 2016-08-17 | — | — | EP | disclosed |
| EP-2274278-B1 | NEW PROCESS FOR THE PREPARATIION OF CYCLOHEXANECARBOXYLIC ACID DERICATIVES | HOFFMANN LA ROCHE (CH) | 2016-08-17 | — | — | EP | disclosed |
| US-20160200672-A1 | NEW PROCESS | HOFFMANN-LA ROCHE INC. | 2016-07-14 | — | — | US | disclosed |
| CN-101981001-B | Prepare the new method of naphthenic acid derivant | 弗·哈夫曼-拉罗切有限公司 | 2016-06-08 | — | — | CN | disclosed |
| US-20150361034-A1 | NEW PROCESS | HOFFMANN-LA ROCHE INC. | 2015-12-17 | — | — | US | disclosed |
| EP-2616433-B1 | PROCESS FOR PREPARING A CYCLOHEXANECARBONITRILE DERIVATIVE | HOFFMANN LA ROCHE (CH) | 2015-12-09 | — | — | EP | disclosed |
| EP-2274264-A1 | NEW PROCESS FOR THE PREPARATION OF CYCLOHEXANECARBOXYLIC ACID DERIVATIVES VIA THE CORRESPONDING CYCLOHEXANECARBOXAMIDE DERIVATIVE | F. Hoffmann-La Roche AG (CH) | 2011-01-19 | — | — | EP | disclosed |
| EP-2274278-A1 | NEW PROCESS FOR THE PREPARATIION OF CYCLOHEXANECARBOXYLIC ACID DERICATIVES | F. Hoffmann-La Roche AG (CH) | 2011-01-19 | — | — | EP | disclosed |
| US-7858823-B2 | Process for cyclohexanecarboxylic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-20090253927-A1 | PROCESS FOR CYCLOHEXANECARBOXYLIC ACID DERIVATIVES | HOFFMANN-LA ROCHE, INC. | 2009-10-08 | — | — | US | disclosed |
| WO-2009121788-A1 | NEW PROCESS FOR THE PREPARATIION OF CYCLOHEXANECARBOXYLIC ACID DERICATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009121789-A1 | NEW PROCESS FOR THE PREPARATION OF CYCLOHEXANECARBOXYLIC ACID DERIVATIVES VIA THE CORRESPONDING CYCLOHEXANECARBOXAMIDE DERIVATIVE | F. HOFFMANN-LA ROCHE AG (CH) | 2009-10-08 | — | — | WO | disclosed |
| US-20090253928-A1 | PREPARATION FOR A CYCLOHEXANECARBOXYLIC ACID DERIVATIVE AND INTERMEDIATES | HOFFMANN-LA ROCHE, INC. | 2009-10-08 | — | — | US | disclosed |
| US-20090253928-A1 | PREPARATION FOR A CYCLOHEXANECARBOXYLIC ACID DERIVATIVE AND INTERMEDIATES | HOFFMANN-LA ROCHE, INC. | 2009-10-08 | — | — | US | disclosed |
| US-20090253928-A1 | PREPARATION FOR A CYCLOHEXANECARBOXYLIC ACID DERIVATIVE AND INTERMEDIATES | HOFFMANN-LA ROCHE, INC. | 2009-10-08 | — | — | US | disclosed |
| WO-2009121788-A1 | NEW PROCESS FOR THE PREPARATIION OF CYCLOHEXANECARBOXYLIC ACID DERICATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200672-A1 | NEW PROCESS | CYP4A11, UGT1A1, CYP11B1 | CETP 565/4885ALDH1A1 343/4885 |
| US-20150361034-A1 | NEW PROCESS | CYP4A11, UGT1A1, CYP11B1 | CETP 565/4885ALDH1A1 343/4885 |
| US-20090253927-A1 | PROCESS FOR CYCLOHEXANECARBOXYLIC ACID DERIVATIVES | CYP2C9, CYP51A1, CYP2B6 | CETP 1190/4885ALDH1A1 166/4885 |
| US-20090253928-A1 | PREPARATION FOR A CYCLOHEXANECARBOXYLIC ACID DERIVATIVE AND INTERMEDIATES | CYP2A13, CYP1A1, CYP2C19 | CETP 1060/4885ALDH1A1 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.