Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299703 | 1.00 | ALDH1A1 (0.40) | ALDH1A1GPR35PDE4A | |
| SCHEMBL14533547 | 1.00 | ALDH1A1 (0.40) | ALDH1A1GPR35PDE4A | |
| SCHEMBL2292115 | 0.97 | — | — | |
| SCHEMBL2292342 | 0.92 | — | — | |
| Acetic Acid SCHEMBL9843655 | 0.87 | ALDH1A1 (0.37) | ALDH1A1GPR35 | |
| SCHEMBL2288386 | 0.86 | — | — | |
| SCHEMBL11373490 | 0.80 | NPC1 (0.39) | ALDH1A1PDE4A | |
| SCHEMBL2154595 | 0.78 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL2154404 | 0.78 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL7764816 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228463-A1 | SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME | GENENTECH, INC. (US) | 2024-07-11 | — | — | US | disclosed |
| US-20220185809-A1 | SUBSTITUTED 2-MORPHOLINOPYRIDINE DERIVATIVES AS ATR KINASE INHIBITORS | REPARE THERAPEUTICS INC. (CA) | 2022-06-16 | — | — | US | disclosed |
| US-20220024906-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2022-01-27 | — | — | US | disclosed |
| US-20210177856-A1 | USE OF ATR INHIBITORS IN COMBINATION WITH PARP INHIBITORS | REPARE THERAPEUTICS INC. (CA) | 2021-06-17 | — | — | US | disclosed |
| US-20190031607-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2019-01-31 | — | — | US | disclosed |
| CN-106083927-B | Phosphino- amidine compound, metal complex, antigravity system and their oligomeric or olefin polymerization purposes | 切弗朗菲利浦化学公司 | 2018-10-26 | — | — | CN | disclosed |
| CN-106083927-A | Phosphinyl amidine compound, metal complex, antigravity system and their oligomeric or purposes of olefin polymerization | 切弗朗菲利浦化学公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-102781949-B | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use for oligomerizing or polymerizing olefins | 切弗朗菲利浦化学公司 | 2016-07-06 | — | — | CN | disclosed |
| US-20160024004-A1 | NOVEL ANTIVIRAL AGENTS AGAINST HBV INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-28 | — | — | US | disclosed |
| CN-102781949-A | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use for oligomerizing or polymerizing olefins | CHEVRON PHILLIPS CHEMICAL CO | 2012-11-14 | — | — | CN | disclosed |
| US-20100137445-A1 | PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD | SUMITOMO CHEMICAL COMPANY ,LIMITED | 2010-06-03 | — | — | US | disclosed |
| EP-2179651-A1 | PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD | Sumitomo Chemical Company, Limited (JP) | 2010-04-28 | — | — | EP | disclosed |
| EP-2174931-A1 | AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-04-14 | — | — | EP | disclosed |
| US-20100069499-A1 | AMIDE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100056640-A1 | AMIDE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2151431-A1 | AMIDE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2010-02-10 | — | — | EP | disclosed |
| EP-2143709-A1 | AMIDE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2010-01-13 | — | — | EP | disclosed |
| US-7442834-B2 | Process suitable for industrial scale production of gabapentin | ZHEJIANG CHIRAL MEDICINE CHEMICALS CO., LTD. (CN) | 2008-10-28 | — | — | US | disclosed |
| WO-2008004698-A2 | PYRAZOLO [1, 5-A] PYRIMIDINE COMPOUNDS AS CB1 RECEPTOR ANTAGONIST | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-01-10 | — | — | WO | disclosed |
| US-4283420-A | ANTICONVULSANTS, ANTIANAPHYLACTIC AGENTS, ANTIPSYCHOTIC AGENTS | LABAZ (FR) | 1981-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024004-A1 | NOVEL ANTIVIRAL AGENTS AGAINST HBV INFECTION | HAVCR2, EIF2AK2, NR1H4 | ALDH1A1 2569/4885GPR35 817/4885PDE4A 2596/4885 |
| US-20220024906-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | ALDH1A1 4654/4885GPR35 522/4885PDE4A 96/4885 |
| US-20100056640-A1 | AMIDE COMPOUND AND USE THEREOF | NAT1, AGXT, HAX1 | ALDH1A1 2983/4885GPR35 4093/4885PDE4A 1427/4885 |
| US-20210177856-A1 | USE OF ATR INHIBITORS IN COMBINATION WITH PARP INHIBITORS | ATR, MRE11, PARP2 | ALDH1A1 4193/4885GPR35 4358/4885PDE4A 3331/4885 |
| US-20190031607-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | RDX, C1R, MTX1 | ALDH1A1 1155/4885GPR35 2925/4885PDE4A 449/4885 |
| US-20100069499-A1 | AMIDE COMPOUND AND USE THEREOF | CBR1, CBR3, GBA1 | ALDH1A1 2111/4885GPR35 3118/4885PDE4A 3723/4885 |
| US-20240228463-A1 | SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME | CACNA1I, CACNA1B, CACNA1C | ALDH1A1 1555/4885GPR35 1290/4885PDE4A 653/4885 |
| US-20220185809-A1 | SUBSTITUTED 2-MORPHOLINOPYRIDINE DERIVATIVES AS ATR KINASE INHIBITORS | ATR, CHEK2, CHEK1 | ALDH1A1 3792/4885GPR35 4096/4885PDE4A 1285/4885 |
| US-20100137445-A1 | PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD | CBR3, CBR1, HDHD5 | ALDH1A1 2677/4885GPR35 3772/4885PDE4A 3354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.